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With chapters written by faculty and researchers from prestigious institutions working directly in hematopoiesis and advanced areas of biology, the volume offers a comprehensive overview of the regulation of blood cell development, epigenetic mechanisms, and regulatory non-coding RNAs. It presents concepts related to regulation of hematopoietic stem cell development, as well as survival, proliferation, and differentiation. It also discusses the microenvironmental niche where stem cells exist and develop into distinct blood cell types. A model system used to study non-coding RNA functions along with the transformation of normal cells into cancer cell is elaborated on as well. Key features of the book: Details how to utilize the available investigative tools and techniques to isolate and study single blood cells in different model systems Discusses the epigenetics of hematopoiesis Considers the clinical outcomes of defective hematopoiesis Describes hematopoiesis and cancer stem cells Looks at hematopoiesis in relation to specific diseases, such as minimal residual disease (MRD) and leukemia This book provides valuable information related to developments in hematopoiesis that will help understand the basics of hematopoiesis and the clinical treatment of blood diseases. 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