Cancer through the Lens of Evolution and Ecology

Cancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity;

2) how scarce resources influence cancer therapy resistance;

3) how predator-prey dynamics are mirrored in immune-cancer cross-talk;

4) how cancer cells parallel niche construction theory;

5) how changing fitness landscapes enable cancer growth; 

6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.
Key Features

▶︎ Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated.
▶︎ Offers insights from leading scholars in cancer biology, ecology and evolutionary biology.
▶︎ Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment.
▶︎ Integrates basic and applied sciences of oncology and evolutionary biology.
Product Details
Publisher ‏ : ‎ CRC Press; 1st edition (July 5, 2024)
Language ‏ : ‎ English
Paperback ‏ : ‎ 214 pages
ISBN-10 ‏ : ‎ 1032310774
ISBN-13 ‏ : ‎ 978-1032310770